Researchers from University of Leeds’ School of Chemistry has made interesting discovery of a peptide known as P 11-4 that capable to construct into fibers under certain conditions. The good news is, when the peptide P 11-4 is applied to a tooth, the fluid spees into the micro-pores that form when the acid produced by bacteria in plaque dissolves the teeth.

Unlike another drill-free cavity solution such as DMG cavity infiltration system that utilize a gel to open up the pores of a cavity so it can be filled with a resin, the revolutionary peptide-based fluid P 11-4 once inside the micro-pores will spontaneously forms a gel that provides a ‘scaffold’ that attracts calcium and regenerates the tooth’s mineral from within in order to provide natural and pain-free repair of the damaged tooth.


According to the Professor Jennifer Kirkham from University of Leeds Dental Institute that lead the researchers in developement of the new peptide P 11-4 said, it may sound too good to be true, but they are essentially helping acid-damaged teeth to regenerate themselves. A totally natural and non-surgical repair process that entirely pain-free.

Funded by Switzerland-based start-up credentis AG, the new peptide research project has licensed the technology and plans to introduce P 11-4 to dentists worldwide.

In near future, no more trauma or fear of for getting your teeth examine by your dentist, as the new pain-free method would save the smile of millions worldwide. 🙂

[ Source: Univeristy of Leeds ; Credentis ]